Insights

In-depth articles and expert analysis from pharmaceutical leaders, exploring advances in life sciences, drug development and the trends shaping healthcare innovation.

Pharmatica image of a Pharmaceutical research laboratory illustrating Good Laboratory Practice, controlled experiments, documentation, and data integrity in preclinical R&D.

Preclinical Development Biomedical R&D Pharma Policy

Good Laboratory Practice Always Sets the R&D Standard

Nicole Dale

Pharmatica image representing the AlphaGenome Atlas genomic AI map with single-nucleotide variant prediction across the human genome.

AI Drug Discovery AI & Machine Learning Research Informatics

AlphaGenome Atlas: Mapping Every Possible DNA Variant

Nicole Dale

Pharmatica image showing planning for FDA Expedited IND Pilot application to support faster preparation for first-in-human clinical trials.

Regulatory Pathways Regulatory Strategy Clinical Trial Regulation

FDA Expedited IND Pilot Targets Faster First-In-Human Trials

Nicole Dale

Pharmatica close-up image of a young child wearing a white T-shirt with a Rare Disease Day badge, seated in a bright clinical home environment with red medical devices in the background, representing rare disease care, patient independence, and humanitarian medical technology.

CDRH Rare Disease Impact Initiative Sets New FDA Focus

Pharmatica image of an ADC manufacturing facility showing antibody-drug conjugate drug product production and pharmaceutical processing equipment.

More Than Conjugation: ADC Manufacturing

Pharmatica GLP-1 obesity clinical development visual showing metabolic therapy, clinical research, and evidence generation.

GLP-1 Obesity Evidence Is Changing Clinical Development

Pharmatica editorial close‑up of FDA regulatory submission materials for diabetes devices, featuring a Libre glucose sensor, red insulin pen, and red office stamps and pens on a beige folder labeled, ‘U.S. Food & Drug Administration (FDA) – Regulatory Submission Diabetes Division,’ representing medical‑device approval and diabetes‑management technology.

Libre Duo FDA Authorisation Through De Novo Pathway

Explore All Insights

Browse our complete library of expert articles and analysis. Explore content across science, policy and life sciences innovation.

Nicole Dale

Throne Science: Passive Health Monitoring in the Bathroom

Pharmatica image of an AI-powered smart sensor for passive health monitoring, showing gut health and connected digital health data.

Read about how Throne Science is advancing passive health monitoring with AI-powered sensing that automatically captures daily toilet habit data.

Nicole Dale

Data Integrity and ALCOA Principles in Pharma Manufacturing

Pharmatica image representing ALCOA+ data integrity principles for pharmaceutical manufacturing and life sciences documentation, shown with glowing data connections.

Data integrity and ALCOA principles are under new pressure as digital twins, AI, and continuous manufacturing reshape pharma production and quality control.

Nicole Dale

FDA Generic Peptides Guidance Sets New Expectations

Pharmatica visual of the FDA generic peptides guidance showing peptide molecular structure and regulatory assessment of generic peptide medicines.

Revised FDA draft guidance for generic peptide products updates expectations for ANDAs, impurities, structure, immune response, and biological activity.

Nicole Dale

Cold Chain Optimisation by Rethinking Pharma Logistics

Pharmatica image of pharmaceutical cold chain optimisation using temperature-controlled logistics, monitoring, and supply chain technology.

See how cold chain optimisation can reduce pharmaceutical logistics costs, emissions, and product risk by modelling uncertainty across storage and distribution.

Nicole Dale

The Ethics of Decentralised Clinical Trials

Pharmatica image representing decentralised clinical trials using remote monitoring, digital health technology, and telehealth to connect clinical research participants with investigators.

Ethical obligations in decentralised clinical trials extend beyond consent and privacy. Sponsors must protect safety, scientific validity, equity, and oversight.

Nicole Dale

Nanocarriers Target the Eye for Better Ocular Drug Delivery

Pharmatica image representing ocular drug delivery using nanocarriers to improve therapeutic targeting of the eye and retinal tissues.

Ocular drug delivery faces major biological barriers. Nanocarriers could improve bioavailability, tissue targeting, controlled release, and treatment for difficult eye diseases.

Nicole Dale

AI Creates New Viruses? Not Quite. AI-Designed Bacteriophages

Pharmatica image of AI-designed bacteriophage research in a biotech laboratory showing genome analysis, AI genome design, and phage development.

AI-designed bacteriophages show how genome models could create new antibacterial therapies while forcing pharma to rethink biological AI governance and biosecurity.

Nicole Dale

What is a Continuous Improvement Mindset in Pharma Manufacturing?

Pharmatica photorealistic image of a modern pharmaceutical manufacturing facility with stainless steel production equipment and digital quality monitoring systems supporting continuous improvement.

A continuous improvement mindset strengthens pharma manufacturing quality. See how quality management and CGMP inspections can sustain continuous improvement.

Nicole Dale

WHOOP x Natural Cycles: Wearable Health Data x Women’s Health

Pharmatica image that represents a WHOOP wearable and Natural Cycles smartphone app, illustrating wearable health data, women's health monitoring, and digital health technology.

WHOOP and Natural Cycles show how wearable health data is moving into regulated digital health, creating new opportunities for women’s health and pharma.

Nicole Dale

Blockchain Adds a Trusted Data Layer in Pharma Manufacturing

Pharmatica image of a realistic pharmaceutical manufacturing environment featuring interconnected stainless‑steel bioreactors and tanks linked by glowing yellow blockchain data pathways and hexagonal nodes with padlock icons, symbolising secure data integrity, traceability, and AI‑driven innovation in pharma manufacturing.

Blockchain in pharma manufacturing could strengthen traceability, data integrity, and supply-chain visibility. Pharmatica examines the evidence and barriers.

Nicole Dale

Making Flexibility Work with Adaptive Clinical Trials

Pharmatica image showing two clinical researchers in white laboratory coats reviewing trial data on a digital tablet in a modern pharmaceutical research environment. The background shows laboratory equipment and translucent scientific graphics, symbolising adaptive clinical trial design, evidence‑driven decision‑making, and digital data integration in clinical development.

Adaptive clinical trials can improve efficiency, reduce patient burden, and support faster development through structured, evidence-based flexibility.

Nicole Dale

Collaborating for R&D Success in Drug Discovery

Pharmatica realistic representation of collaboration in drug discovery showing interlocking green and blue puzzle pieces with a DNA helix emerging from their center, capsules in front, a glowing molecular data screen behind, and a 3D molecular model to the right on a bright white background.

Collaboration in drug discovery can shape pharma R&D success. Explore the evidence on pharma partnerships, knowledge sharing, governance, and innovation.

Topic