Clinical Development

Understand clinical trials, development strategy and regulatory pathways shaping drug approval.

Nicole Dale

GLP-1 Obesity Evidence Is Changing Clinical Development

Pharmatica GLP-1 obesity clinical development visual showing metabolic therapy, clinical research, and evidence generation.

GLP-1 obesity clinical evidence is reshaping drug development as efficacy, safety, cardiovascular outcomes, and treatment durability become critical.

Nicole Dale

LLMs in Clinical Trial Screening: Can AI Find the Right Patients?

Pharmatica image that represents LLMs in clinical trial screening using AI to analyse clinical data and identify potential trial matches.

Explore how LLMs in clinical trial screening could improve patient matching, and why human oversight, data quality, and trust remain essential.

Nicole Dale

Endpoints in Gynaecological Oncology Clinical Trials

Pharmatica photo‑realistic editorial image of a healthcare professional discussing clinical data with a patient in a modern hospital setting, symbolising compassionate care and digital innovation in gynaecological oncology trials and clinical development.

Gynaecological oncology clinical trials reveal that survival gains and trial design do not always align. Here is what clinical development teams should learn.

Nicole Dale

Digital Health Technologies in Clinical Drug Development

Pharmatica image of digital health technologies collecting clinical trial data for drug development.

Digital health technologies in clinical drug development need more than data. Explore validation, standards, digital endpoints, patient value, and regulation.

Nicole Dale

RCT Recruitment Prediction: Better Statistics, Better Trials

Pharmatica image of RCT recruitment prediction showing clinical trial sites, patient enrolment pathways, statistical forecasting, and recruitment targets.

RCT recruitment prediction can improve trial planning by using Poisson and Bayesian models to estimate enrolment rates, uncertainty, and recruitment risk.

Nicole Dale

Enriched Clinical Trial Design: Who Gets Left Behind?

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Enriched clinical trial design can improve trial efficiency, but may exclude patients from the evidence base. Explore the implications for clinical development.

Nicole Dale

EHR Patient Recruitment Gets A Reality Check

Pharmatica image representing EHR patient recruitment technology connecting electronic health records, clinical trial eligibility data, and patient-trial matching.

EHR patient recruitment could improve clinical trial matching, but workflow integration, data quality, interoperability, and AI validation remain key challenges.

Nicole Dale

The Ethics of Decentralised Clinical Trials

Pharmatica image representing decentralised clinical trials using remote monitoring, digital health technology, and telehealth to connect clinical research participants with investigators.

Ethical obligations in decentralised clinical trials extend beyond consent and privacy. Sponsors must protect safety, scientific validity, equity, and oversight.

Nicole Dale

Making Flexibility Work with Adaptive Clinical Trials

Pharmatica image showing two clinical researchers in white laboratory coats reviewing trial data on a digital tablet in a modern pharmaceutical research environment. The background shows laboratory equipment and translucent scientific graphics, symbolising adaptive clinical trial design, evidence‑driven decision‑making, and digital data integration in clinical development.

Adaptive clinical trials can improve efficiency, reduce patient burden, and support faster development through structured, evidence-based flexibility.

Nicole Dale

Growing Patient and Public Involvement in Clinical Trials

Pharmatica image representing public and patient involvement in clinical trials. Shows a diverse group of clinical trial participants and researchers engaged in collaborative discussion around a bright white table in a modern research environment. A female doctor in a white lab coat leads the conversation, surrounded by older and younger participants of different ethnic backgrounds. Digital screens in the background display molecular structures and clinical data in blue tones, symbolising transparency.

Patient and public involvement in clinical trials improves study design. Learn why better reporting is essential for transparent, patient-centred research.

Nicole Dale

The Latest Evidence on Informed Consent in Clinical Trials

Pharmatica image representing informed consent in clinical trials with digital eConsent technology, participant engagement, clinical research ethics, transparent communication, and modern clinical trial management.

A recent systematic review reveals incredible detail about informed consent in clinical trials, participant understanding, and trial quality. Find out now.

Nicole Dale

Optimising Clinical Trial Data Collection for Better Decisions

Optimising clinical trial data collection Pharmatica image representing fit-for-purpose evidence generation.

Learn how optimised clinical trial data collection improves data quality, reduces protocol and patient burden, and supports smarter clinical development.

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