Drug Design & Delivery

Nicole Dale

Why Does the True Impact of AI in Drug Discovery Lag?

Pharmatica image showing dense green data nodes that converge on one illuminated point, symbolising AI in drug discovery.

AI in drug discovery keeps making headlines, but clinical success rates barely move. A new Nature Reviews Perspective explains why, and what pharma should do next.

Nicole Dale

Why Formulation Development Now Starts With Manufacturing

Pharmatica image of pharmaceutical formulation development connecting drug formulation science with advanced manufacturing and process control.

Formulation development is moving beyond drug delivery to shape manufacturing, quality, scale-up, and supply resilience across modern pharmaceutical operations.

Nicole Dale

Nanocarriers Target the Eye for Better Ocular Drug Delivery

Pharmatica image representing ocular drug delivery using nanocarriers to improve therapeutic targeting of the eye and retinal tissues.

Ocular drug delivery faces major biological barriers. Nanocarriers could improve bioavailability, tissue targeting, controlled release, and treatment for difficult eye diseases.

Nicole Dale

Collaborating for R&D Success in Drug Discovery

Pharmatica realistic representation of collaboration in drug discovery showing interlocking green and blue puzzle pieces with a DNA helix emerging from their center, capsules in front, a glowing molecular data screen behind, and a 3D molecular model to the right on a bright white background.

Collaboration in drug discovery can shape pharma R&D success. Explore the evidence on pharma partnerships, knowledge sharing, governance, and innovation.

Nicole Dale

Psychedelic Drug Discovery Gets a New Preclinical Framework

Pharmatica detailed rendering of a neuron firing electrical impulses through dendrites and axons in vivid green tones, symbolising neural connectivity and communication in psychedelic drug discovery, neuroplasticity, 5-HT2A receptor pharmacology, CNS drug development, psychoplastogens, and therapeutic neuroscience research.

Find out how psychedelic drug discovery is evolving through receptor pharmacology, behavioural science, and neuroplasticity to develop safer CNS therapeutics.

Nicole Dale

Could Dry mRNA Vaccine Patches Eliminate the Cold Chain?

Pharmatica image representing dry mRNA vaccine patches showing cold chain-free RNA therapeutic delivery, lipid nanoparticle stability, pharmaceutical manufacturing, and advanced vaccine distribution technology.

Discover how dry mRNA vaccine patches could reduce cold chain dependence, improve vaccine stability, and reshape pharmaceutical manufacturing and distribution.

Nicole Dale

Using Machine Learning for Lipid Nanoparticle Design

Machine learning for lipid nanoparticles illustrating AI-driven optimisation of lipid nanoparticle formulations for mRNA drug delivery, RNA therapeutics, nanomedicine, and next-generation drug discovery.

Read about machine learning for lipid nanoparticle design used to improve cell, gene, and RNA drug delivery and help optimise next-generation therapeutics.